Open Access
An Update on Patent Ductus Arteriosus and What is Coming Next
Author(s) -
Ömer Erdeve,
Emel Okulu,
Yogen Singh,
Richard Sindelar,
Mehmet Yekta Öncel,
Gianluca Terrin,
Giovanni Boscarino,
Ali Bülbül,
Hannes Sallmon,
Begüm Atasay,
Fahri Ovalı,
Ronald I. Clyman
Publication year - 2022
Publication title -
pubmed central
Language(s) - English
Resource type - Journals
pISSN - 2757-6256
DOI - 10.5152/turkarchpediatr.2022.21361
Subject(s) - ductus arteriosus , medicine , cardiology , pediatrics , intensive care medicine
Patent ductus arteriosus is the most common cardiovascular condition in preterm infants. There is a significant uncertainty about when and how to close ductus arteriosus in preterm infants due to a high spontaneous closure rate even in very immature preterm infants. Diagnosis and management of patent ductus arteriosus remain a challenge for both neonatologists and pediatric cardiologists. Researchers have tried to define a balance between an expectant approach and active treatment in selected infants. This review aimed to focus on the pathophysiology and management of patent ductus arteriosus and to make suggestions about approaches that might eliminate the association of morbidities with patent ductus arteriosus.