Open AccessXRCC1 Gene Polymorphisms and miR-21 Expression in Patients with Colorectal Carcinoma
Author(s) -
Hanan Fouad,
Dina Sabry,
Heba Morsi,
Hany Shehab,
Naglaa F. Abuzaid
Publication year - 2017
Publication title -
the eurasian journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.337
H-Index - 13
eISSN - 1308-8742
pISSN - 1308-8734
DOI - 10.5152/eurasianjmed.2017.17021
Subject(s) - xrcc1 , medicine , genotype , colorectal cancer , oncology , microrna , cancer , gene , single nucleotide polymorphism , genetics , biology
The objectives of this study were to evaluate the impact of two X-ray repair cross complementing 1 (XRCC1) gene polymorphisms (Arg194Trp and Arg399Gln) on the risk of development of colorectal cancer (CRC) and to assess the expression levels of microRNA-21 (miR-21) in CRC patients.