Microwave Mediated Synthesis of Novel 1,3,5-Triazine Derivative and their Biological Evaluation
Author(s) -
Krishn Kumar Barmase,
Deepak Kumar Basedia,
Balkrishna Dubey
Publication year - 2021
Publication title -
international journal of research in engineering science and management
Language(s) - English
Resource type - Journals
ISSN - 2581-5792
DOI - 10.47607/ijresm.2020.433
Subject(s) - cyanuric chloride , triazine , chemistry , derivative (finance) , antibacterial activity , combinatorial chemistry , 1,3,5 triazine , antifungal , yield (engineering) , chloride , organic chemistry , bacteria , microbiology and biotechnology , materials science , biology , economics , genetics , financial economics , metallurgy
1,3,5-Triazine derivative are synthesized by replacement of chloride ions of Cyanuric chloride and 1,3,5-Triazine derivative are showing promising biologically activity such as Antibacterial, Antifungal, Antimalarial, Antivirus, Anticancer that’s why interest of researches on synthesis of 1,3,5-Triazine derivatives always in focused. The present study reported the synthesis of 2,4,6-Trisubstituted 1,3,5-Triazine derivatives by Microwave mediated Method which gave the desired result in less time with higher yield. The structure of 1,3,5-Triazine derivatives have been elucidated by Spectral of IR, NMR and MASS. The derivative of 1,3,5-Triazine are evaluated for their In vitro Antibacterial activity against Gram Positive and Gram Negative Bacterial species and shown good Antibacterial effect.
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