Open AccessA multicenter observational study on Medication-Related Osteonecrosis of the Jaw (MRONJ) in advanced cancer and myeloma patients of a cancer network in North-Western Italy
Author(s) -
Vittorio Fusco,
Marco Cabras,
Francesco Erovigni,
Alessandro Dell’Acqua,
Pg Arduino,
Monica Pentenero,
Paolo Appendino,
L. Basano,
F. Della Ferrera,
Antonella Fasciolo,
M Caka,
Mario Migliario
Publication year - 2021
Publication title -
medicina oral, patología oral y cirugía bucal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 56
eISSN - 1698-6946
pISSN - 1698-4447
DOI - 10.4317/medoral.24318
Subject(s) - medicine , observational study , cancer , osteonecrosis of the jaw , multiple myeloma , oncology , bisphosphonate , osteoporosis
Incidence of Medication-Related Osteonecrosis of the Jaw (MRONJ) related to cancer and myeloma treatments is undetermined, with scarce data varying from 2 to 7.8/million/year in limited investigated populations. A 9-years [2009-2018] regional-wide survey was conducted, deploying the North-Western Italy Cancer Network ("Rete Oncologica Piemonte e Valle d'Aosta"), to assess number and main characteristics of MRONJ cases among myeloma/cancer patients, within a population of 4.5 million inhabitants.