Open AccessEpigenetics and periodontics: A systematic review
Author(s) -
Almiñana-Pastor Pj,
Montserrat Boronat-Catalá,
Pablo Micó-Martínez,
Carlos Bellot-Arcís,
Andrés López-Roldán,
Alpiste-Illueca Fm
Publication year - 2019
Publication title -
medicina oral, patología oral y cirugía bucal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 56
eISSN - 1698-6946
pISSN - 1698-4447
DOI - 10.4317/medoral.23008
Subject(s) - epigenetics , periodontology , bioinformatics , periodontium , dynamism , dna methylation , medicine , computational biology , biology , pathology , gene expression , dentistry , genetics , gene , physics , quantum mechanics
Despite decades of research, our knowledge of several important aspects of periodontal pathogenesis remains incomplete. Epigenetics allows to perform dynamic analysis of different variations in gene expression, providing this great advantage to the static measurement provided by genetic markers. The aim of this systematic review is to analyze the possible relationships between different epigenetic mechanisms and periodontal diseases, and to assess their potential use as biomarkers of periodontitis.