Open AccessThe Remarkable Beneficial Effect of Adding Oral Simvastatin to Topical Betamethasone for Treatment of Psoriasis: A Double-blind, Randomized, Placebo-controlled Study
Author(s) -
Mitra Naseri,
A Hadipour,
Mozhdeh Sepaskhah,
Mohammad-Hassan Namazi
Publication year - 2010
Publication title -
nigerian journal of medicine/the nigerian journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2667-0526
pISSN - 1115-2613
DOI - 10.4314/njm.v19i1.54216
Subject(s) - simvastatin , medicine , psoriasis , betamethasone , placebo , psoriasis area and severity index , therapeutic effect , randomized controlled trial , dermatology , clinical trial , topical steroid , pharmacology , pathology , alternative medicine
Psoriasis is a common chronic inflammatory disease with unpredictable prognosis. Given the immunomodulatory effects of statins, the present study was conducted to determine whether the addition of orally administered simvastatin to the topical betamethasone, a standard antipsoriatic treatment, can produce a more powerful therapeutic response against this clinical conundrum.