A Combination of Virgin Coconut Oil and Extra Virgin Olive Oil Elicits Superior Protection Against Doxorubicin Cardiotoxicity in Rats | Zendy

Andi Ulfiana Utari | Zendy; Yulia Yusrini Djabir | Zendy; Bogie Putra Palinggi | Zendy

Open Access

A Combination of Virgin Coconut Oil and Extra Virgin Olive Oil Elicits Superior Protection Against Doxorubicin Cardiotoxicity in Rats

Author(s) -

Andi Ulfiana Utari,

Yulia Yusrini Djabir,

Bogie Putra Palinggi

Publication year - 2021

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.galenos.2021.37998

Subject(s) - cardiotoxicity , olive oil , coconut oil , doxorubicin , toxicology , pharmacology , traditional medicine , food science , biology , medicine , toxicity , chemotherapy

The use of the chemotherapy agent doxorubicin (DOX) is associated with free radical formation that may lead to cardiotoxicity. Virgin coconut oil (VCO) and extra virgin olive oil (EVOO) are plant-based oil that is rich in antioxidants. This study examined the protective effects of VCO and EVOO combination to reduce DOX acute cardiotoxicity in rats.

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