Open Accessmpact of Concomitant Aberrant CD200 and BCL2 Overexpression on Outcome of Acute Myeloid Leukemia: A Cohort Study from a Single Center
Author(s) -
Mario Tiribelli,
Angela Michelutti,
Margherita Cavallin,
Sara Di Giusto,
Renato Fanin,
D. Doḿınguez Damiani
Publication year - 2021
Publication title -
turkish journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.351
H-Index - 16
ISSN - 1300-7777
DOI - 10.4274/tjh.galenos.2021.2020.0728
Subject(s) - medicine , concomitant , cohort , myeloid leukemia , single center , center (category theory) , myeloid , outcome (game theory) , oncology , chemistry , mathematics , mathematical economics , crystallography
CD200 and BCL2 overexpression is independently associated with inferior survival in acute myeloid leukemia (AML), and these two factors are frequently co-expressed; however, no data are available on the role of concomitant aberrant CD200 and BCL2 expression on outcome of AML patients. We aimed to elucidate the prognostic role of CD200/BCL2 co-expression and its association with specific leukemia subsets.