Open AccessAllogeneic Hematopoietic Stem Cell Transplantation in Extranodal Natural Killer/T-cell Lymphoma
Author(s) -
Yin-yin Peng,
Yufeng Xiong,
Lixia Zhang,
Jing Wang,
Hongbin Zhang,
Qing Xiao,
Shuliang Guo
Publication year - 2021
Publication title -
turkish journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.351
H-Index - 16
ISSN - 1300-7777
DOI - 10.4274/tjh.galenos.2021.2020.0438
Subject(s) - medicine , lymphoma , hematopoietic stem cell transplantation , transplantation , stem cell , hematopoietic cell , haematopoiesis , immunology , biology , genetics
Extranodal NK/T-cell lymphoma (ENKL) is aggressive and resistant to chemotherapy and radiotherapy. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment for high-risk lymphomas owing to its associated graft-versus-lymphoma (GVL) effect. However, its application to ENKL is limited. We aim to summarize the characteristics of allo-HSCT for ENKL and, more importantly, evaluate whether allo-HSCT could offer any benefits for ENKL.