Open AccessCardiac risk factors limiting survival to liver transplantation in patients with nonalcoholic fatty liver disease
Author(s) -
Michael Delicce,
Joseph Mauch,
Abel Joseph,
Ruishen Lyu,
Heather Kren,
Rose Bartow,
Donna Ferchill,
Maan Fares,
Jamilé Wakim-Fleming
Publication year - 2022
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v14.i7.1398
Subject(s) - medicine , nonalcoholic fatty liver disease , liver transplantation , coronary artery disease , liver disease , transplantation , valvular heart disease , fatty liver , cardiology , disease
Nonalcoholic fatty liver disease (NAFLD) describes the hepatic manifestations of metabolic syndrome, which is estimated to affect 25% of adults, and currently represents the second most common indication for liver transplant in the United States. Studies have shown that patients with NAFLD are at an increased risk for heart failure, arrhythmia, and coronary artery disease (CAD), which may impact outcomes of liver transplantation. However, it remains unclear whether the presence of cardiac disease affects survival prior to liver transplant. If so, this would represent an important opportunity to optimize cardiac status and improve outcomes before liver transplant.