Open AccessHigh prevalence of occult hepatitis C infection in predialysis patients
Author(s) -
Luís Henrique Bezerra Cavalcanti Sette,
Edmundo Pessoa de Almeida Lopes,
Nathália Campello Guedes dos Anjos,
Lucila Maria Valente,
Stefan Vilges de Oliveira,
Norma LucenaSilva
Publication year - 2019
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v11.i1.109
Subject(s) - medicine , hemodialysis , population , occult , kidney disease , hepatitis c , epidemiology , serology , peripheral blood mononuclear cell , gastroenterology , hepatitis c virus , immunology , antibody , pathology , virus , biochemistry , chemistry , alternative medicine , environmental health , in vitro
Occult hepatitis C virus (HCV) infection (OCI) may be associated with extrahepatic diseases and it is known that the patients with chronic kidney disease (CKD) who are on hemodialysis (HD) present a higher prevalence of this type of infection than the general population, with a worse clinical outcome. However, there are no data in the literature to assess the presence of OCI in patients prior to the initiation of renal replacement therapy (RRT). Therefore, this study aimed to evaluate the occurrence and epidemiological aspects of OCI in patients with Predialysis CKD. We hypothesize that this infection could occur before RRT initiation.