Open AccessProtein expression trends of DNMT1 in gastrointestinal diseases: From benign to precancerous lesions to cancer
Author(s) -
Tianmiao Ma,
Liping Sun,
Ning Dong,
Mingjun Sun,
Yuan Yuan
Publication year - 2019
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v11.i12.1141
Subject(s) - medicine , intestinal metaplasia , gastroenterology , precancerous condition , cancer , intraepithelial neoplasia , atrophic gastritis , immunohistochemistry , colorectal cancer , incidence (geometry) , pathology , gastritis , stomach , prostate cancer , physics , optics
In recent years, the incidence of gastrointestinal (GI) cancer in China has increased annually. Early detection and appropriate therapy are considered to be the key to treat GI cancer. DNMT1 takes an active part in the advancement of GI cancer, which will change as the disease progresses. But its expression characteristics in the dynamic variations of GI carcinogenesis are still unclear.