Open AccessIn Silico Prediction of Molecular Interaction Within PmCBP-VP24 Complex to Understand Initial Instigation of WSSV into Shrimps
Author(s) -
Kanika Yadav,
Ankita Verma,
Ajey Kumar Pathak,
Abhishek Awasthi
Publication year - 2021
Publication title -
genetics of aquatic organisms
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.185
H-Index - 3
ISSN - 2459-1831
DOI - 10.4194/2459-1831-v5_2_05
Subject(s) - shrimp , white spot syndrome , penaeus monodon , in silico , biology , virus , virology , computational biology , fishery , genetics , gene
White Spot Disease is one of the most devastating diseases of shrimps. Molecular interaction between shrimp receptor protein PmCBP (Chitin binding protein of Peneaus monodon) and viral envelop protein VP24 is obligatory for binding of the White Spot Syndrome Virus to the shrimp digestive tract, and failure of this anchoring leads to an ineffectual infection. This is a first study that throws light on the molecular interaction of PmCBP-VP24 complex and provides important clues for initial steps of ingression of the virus into shrimps.