Open AccessClinical Features of Babies Born to Mothers with Oligohydramnios: A Two Years’ Experience
Author(s) -
Xinhua Chen,
Guang Bai,
Theresa O. Scholl
Publication year - 2015
Publication title -
journal of pregnancy and child health
Language(s) - English
Resource type - Journals
ISSN - 2376-127X
DOI - 10.4172/2376-127x.1000215
Subject(s) - dna methylation , methylation , gestation , fetus , andrology , bisulfite , medicine , bisulfite sequencing , gene , obstetrics , gestational age , pregnancy , biology , genetics , gene expression
Preterm delivery and sub-optimal fetal growth are associated with each other and affect both mother and infant. Our aim was to determine (i) whether there are detectable differences in DNA methylation between early and late gestation and (ii) whether changes in DNA methylation from entry are associated with spontaneous preterm delivery with and without reduced fetal growth.