Open AccessCat NPC2, a Newly Identified Allergen, With High Cross-Reactivity to Can f 7
Author(s) -
Dan Zhu,
Lin Li,
Zhi Xu,
Cheng Zhang,
Jin Song Zhang,
Jiandong Sun,
Wei Jiang
Publication year - 2021
Publication title -
allergy, asthma and immunology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 45
eISSN - 2092-7363
pISSN - 2092-7355
DOI - 10.4168/aair.2021.13.1.122
Subject(s) - cross reactivity , allergen , reactivity (psychology) , cross reactions , chemistry , medicine , immunology , allergy , pathology , antibody , alternative medicine
Pet-derived allergens are the common indoor inhalant allergens. Among them, cat and dog allergens constitute more than 80% of animal allergic patients, which greatly affect the quality-of-life of patients and increase the burden of social health care. The aim of this study was to identify Cat-Niemann pick type C2 (NPC2) protein, a homologue of Can f 7, as a new allergen.