Open AccessThe detection of primary and secondary EGFR mutations using droplet digital PCR in patients with nonsmall cell lung cancer
Author(s) -
Moushumi Suryavanshi,
Anurag Mehta,
Manoj Kumar Panigrahi,
Jiten Jaipuria,
Mumtaz Saifi,
Kavita Jain,
Dushyant Kumar,
Haristuti Verma,
Shubham Sharma,
Ullas Batra,
Kumardeep Dutta,
Vineet Talwar,
Dinesh Chandra Doval
Publication year - 2018
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/lungindia.lungindia_472_17
Subject(s) - t790m , medicine , biopsy , digital polymerase chain reaction , liquid biopsy , lung cancer , mutation , pathology , gefitinib , cancer , epidermal growth factor receptor , polymerase chain reaction , biology , gene , genetics
We share our experience of using droplet digital polymerase chain reaction (DdPCR) in liquid biopsy specimens for detecting primary and secondary epidermal growth factor receptor (EGFR) mutations among patients with nonsmall-cell lung cancer who had tissue biopsy initially analyzed for del19, L858R and T790M.