Open AccessEffects of genetic polymorphisms in Vitamin D metabolic pathway on Vitamin D level and asthma control in South Indian patients with bronchial asthma
Author(s) -
M. Rajaram,
Sandhiya Selvarajan,
Revathy Neelamegan,
Sadishkumar Kamalanathan,
Vikneswaran Gunaseelan,
Alphienes Stanley Xavier,
Saibal Das,
V Karthikeyan,
Vinodkumar Saka,
Adithan Chandrasekaran
Publication year - 2019
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/lungindia.lungindia_23_19
Subject(s) - asthma , single nucleotide polymorphism , calcitriol receptor , medicine , vitamin d and neurology , exhaled nitric oxide , vitamin d deficiency , immunology , gene , genotype , genetics , biology , bronchoconstriction
The study was designed to evaluate the single-nucleotide polymorphisms (SNPs) of genes involved in Vitamin D actions (rs2228570) and metabolic pathways (rs2248137 and rs10766197) and their associations with serum 25-hydroxy Vitamin D (25(OH)D) level and asthma control in South Indian patients with bronchial asthma.