Open AccessCorneal oxidative damage in keratoconus cells due to decreased oxidant elimination from modified expression levels of SOD enzymes, PRDX6, SCARA3, CPSF3, and FOXM1
Author(s) -
Shari R. Atilano,
Daniel H Lee,
Paula Sakemi Fukuhara,
Marilyn Chwa,
Anthony B. Nesburn,
Nitin Udar,
M. Cristina Kenney
Publication year - 2019
Publication title -
journal of ophthalmic and vision research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.557
H-Index - 27
eISSN - 2008-2010
pISSN - 2008-322X
DOI - 10.4103/jovr.jovr_80_18
Subject(s) - oxidative stress , sod2 , microbiology and biotechnology , antioxidant , reactive oxygen species , nitric oxide synthase , nadph oxidase , nitric oxide , apocynin , biology , biochemistry , enzyme , superoxide dismutase , endocrinology
To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells) in vitro .