Open AccessComparative evaluation of galactomannan test with bronchoalveolar lavage and serum for the diagnosis of invasive aspergillosis in patients with hematological malignancies
Author(s) -
Ankit Gupta,
Malini R. Capoor,
Trupti Shende,
Bhawna Sharma,
Ritin Mohindra,
Jagdish Chander Suri,
Divyansh Gupta
Publication year - 2017
Publication title -
journal of laboratory physicians
Language(s) - English
Resource type - Journals
eISSN - 0974-7826
pISSN - 0974-2727
DOI - 10.4103/jlp.jlp_127_16
Subject(s) - galactomannan , bronchoalveolar lavage , medicine , aspergillosis , gastroenterology , bronchoscopy , medical diagnosis , receiver operating characteristic , surgery , immunology , pathology , lung
Invasive pulmonary aspergillosis (IPA) is a major cause of morbidity and mortality in patients with hematological malignancies. In recent years, testing for values of galactomannan (GM) in serum and bronchoalveolar lavage (BAL) fluid has been investigated as a diagnostic test for IPA for such patients, but global experience and consensus on optical density (OD) cutoffs, especially for BAL galactomannan remains lacking.