Open AccessBone marrow aspirations in Ewing sarcomas: Are they still necessary? A single-center retrospective analysis and review of the literature
Author(s) -
Bernadette Breitegger,
Lukas A. Holzer,
Christine Beham–Schmid,
Christian Urban,
Bernadette LieglAtzwanger,
Andreas Leithner
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_941_16
Subject(s) - medicine , bone marrow , retrospective cohort study , single center , soft tissue , ewing's sarcoma , sarcoma , pathology , radiology , metastasis , oncology , cancer
Currently, one of the most useful prognostic indicators in Ewing sarcomas (ES) is the presence of metastatic disease at diagnosis. According to various clinical guidelines, the assessment of bone marrow (BM) metastases, using light microscopy examination of bone marrow aspirates and biopsies (BMAB) is mandatory. However, the prognostic value of BM positivity is discussed controversially. Therefore, the primary aim of this study was to retrospectively review BM samples from patients with ES.