Open AccessAssessment of human epidermal growth factor receptor 2/neu gene amplification and expression as a biomarker for radiotherapy and hormonal-treated breast cancer patients in upper Egypt
Author(s) -
Marwa Khairy Essmat,
Mostafa A Abdelwanis,
Eman Mosad,
Tarek K El-Maghraby,
Mohamed I. A. Othman
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_42_17
Subject(s) - breast cancer , radiation therapy , medicine , oncology , chemotherapy , biomarker , cancer , hormonal therapy , her2/neu , biology , biochemistry
Breast cancer plays major public health in Egyptian women. In upper Egypt, There is an increase in the incidence of breast cancer compared to other Egyptian areas without know the reasons. In this study, we aimed to evaluate the potential of HER-2/neu status as one of the important markers to classify the women suffering from breast cancer in upper Egypt and monitoring the responsiveness to different therapies.