Open AccessComparative evaluation of survivin expression in leukoplakia, lichen planus, and oral squamous cell carcinoma
Author(s) -
D Angelin,
Bindu Nair
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_421_19
Subject(s) - survivin , leukoplakia , oral lichen planus , immunohistochemistry , medicine , oral mucosa , oral leukoplakia , carcinoma , basal cell , pathology , oncology , cancer , cancer research
Screening for oral squamous cell carcinomas (OSCCs) and oral premalignant lesions may decrease the devastating morbidity and mortality associated with the disease. This has led to widespread research for the identification of molecular-based biomarkers. Among them, survivin is a recently characterized protein which is a member of the inhibitor of apoptosis family. The aim of this study is evaluating the expression of survivin in oral leukoplakia, oral lichen planus, and OSCC compared with normal mucosa.