Open AccessStage-specific expression analysis of MMP-2 & MMP-9 in laryngeal carcinoma
Author(s) -
Jaimanti Bakshi,
Atul Kumar Goyal,
Virender Singh,
Malay K. Sannigrahi,
Madhu Khullar
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_360_18
Subject(s) - matrix metalloproteinase , larynx , stage (stratigraphy) , metastasis , carcinoma , laryngeal neoplasm , pathology , medicine , biopsy , cancer , extracellular matrix , immunohistochemistry , cancer research , oncology , biology , anatomy , paleontology , microbiology and biotechnology
Both matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) is involved in degradation of extracellular matrix and found to stimulate invasion and metastasis in cancer patients. However, studies on the stage-specific expression of MMPs at different stages of larynx carcinoma are still lacking. In the present study, we compare the expression level of MMP-2 and MMP-9 at different stages of laryngeal carcinoma.