Open AccessSinusoidal obstruction syndrome during treatment for wilms' tumor: A life-threatening complication
Author(s) -
Sidharth Totadri,
Amita Trehan,
Deepak Bansal,
Richa Jain
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_188_16
Subject(s) - medicine , ascites , jaundice , defibrotide , wilms' tumor , gastroenterology , respiratory distress , surgery , transplantation , hematopoietic stem cell transplantation
Survival rates exceed 90% in Wilms' tumor (WT). Actinomycin-D (ACT-D) which is indispensable in the management of WT is associated with the development of sinusoidal obstruction syndrome (SOS), a potentially fatal complication.