Open Access
Cerebral aspergillosis mimicking a neoplasm in an immunocompetent patient
Author(s) -
Zafar Neyaz,
Vivek P. Singh,
Anant Mehrotra,
Manoj Jain
Publication year - 2018
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_393_17
Subject(s) - aspergillosis , etiology , pathology , medicine , neoplasm , dermatology , radiology , immunology
Cerebral aspergillosis mostly presents as single or multiple abscesses with vascular invasion in immunocompromised patients. A rare mass like or tumoral form of cerebral aspergillosis has been described mostly in immunocompetent patients. A 22-year-old-male presented with recurrent attacks of complex partial seizures with secondary generalization, headache, and blurring of vision. Preoperative diagnosis of a cerebral neoplasm was considered in view of solid mass-like enhancement. However, histopathological examination was suggestive of central nervous system aspergillosis. The presence of imaging findings such as T2 hypointensity, irregular frond-like margins, and absence of choline peak may be the clues, which suggest a fungal etiology.