Open AccessPerioperative sildenafil therapy for children with ventricular septal defects and associated pulmonary hypertension undergoing corrective surgery: A randomised clinical trial
Author(s) -
Sidharth Bhasin,
Pooja Gogia,
R. Nair,
Tapan Kumar Sahoo
Publication year - 2017
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/ija.ija_210_17
Subject(s) - medicine , sildenafil , pulmonary hypertension , perioperative , pulmonary artery , anesthesia , cardiopulmonary bypass , placebo , adverse effect , blood pressure , cardiac surgery , intensive care unit , cardiology , surgery , alternative medicine , pathology
Sildenafil is known to reduce pulmonary artery pressure but its role in the perioperative period has not been well studied. We aimed to evaluate the efficacy of sildenafil in controlling post-operative pulmonary hypertension in children with pulmonary hypertension undergoing surgeries for correction of ventricular septal defect.