Open Access“Comparison of nalbuphine hydrochloride and fentanyl as an adjuvant to bupivacaine for spinal anesthesia in lower abdominal surgeries:” A randomized, double-blind study
Author(s) -
Umesh N Prabhakaraiah,
Archana Byadarahalli Narayanappa,
Shivakumar Gurulingaswamy,
Krishna Chaithanya K,
Kiran A Vijaynagar,
Nagarajaiah B Hanumantharayappa,
Diwakar S Ramegowda
Publication year - 2017
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/aer.aer_40_17
Subject(s) - nalbuphine , medicine , fentanyl , anesthesia , spinal anesthesia , bupivacaine , randomized controlled trial , single blind , adjuvant , double blind , surgery , opioid , placebo , alternative medicine , pathology , receptor
Opioids have been favored as adjuvants to local anesthetics during spinal anesthesia. Nalbuphine, a μ-receptor antagonist and ĸ-receptor agonist, seems to be a suitable adjuvant to local anesthetics. The aim of this study was to compare postoperative analgesia and adverse effects of nalbuphine and fentanyl when used as an adjuvant to hyperbaric bupivacaine during spinal anesthesia.