Open AccessShelf life evaluation of Shirishavaleha: A preliminary study
Author(s) -
Harmeet Kaur,
R Galib,
Pradeep Kumar Prajapati
Publication year - 2016
Publication title -
blde university journal of health sciences/blde university journal of health sciences
Language(s) - English
Resource type - Journals
eISSN - 2468-838X
pISSN - 2456-1975
DOI - 10.4103/2468-838x.196099
Subject(s) - shelf life , context (archaeology) , environmental science , relative humidity , sample (material) , chemistry , meteorology , chromatography , food science , geography , archaeology
Context: Shelf life of the drug can be considered up to the period it gets deteriorated and does not get any alteration in its physicochemical state. Every product has definite shelf life, which depends on various physical, chemical, environmental, and biological factors. Ancient seers have clarified shelf life of various compound formulations. However, there is a need to revalidate and ascertain the shelf life of individual formulations by following parameters prevalent in respective scenario. Aim: To evaluate shelf life of Shirishavaleha prepared in the presence of water (SW) and Kanji (SK) as liquid media through accelerated stability study. Subjects and Methods: Physicochemical parameters were measured at 40°C ± 2°C temperature and 75% ±5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months, and average 10% degradation of both the test drug samples was calculated and extrapolated to find the shelf life. Results: The sample prepared in the presence of Kanji (SK) showed more extractive values and sugar contents and found to have longer shelf life (2.6 years) than SW (1.4 years). Conclusion: Shirishavaleha prepared with Kanji (SK) is comparatively more stable than the sample prepared with water (SW)