Open AccessHematoxylin and eosin stain shows a high sensitivity but sub-optimal specificity in demonstrating iron pigment in liver biopsies
Author(s) -
Nasar Alwahaibi,
Azza Sarhan Alkhatri,
Johanes Selva Kumar
Publication year - 2015
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.165365
Subject(s) - stain , h&e stain , pathology , staining , predictive value , medicine , biopsy , pigment , chemistry , organic chemistry
Perls' stain is routinely used to demonstrate iron in liver biopsies. We tested the hypothesis that it may be unnecessary in cases, where no iron or another similar pigment was seen on the routine hematoxylin and eosin (H and E) stained section.