Open AccessCisatracurium in different doses versus atracurium during general anesthesia for abdominal surgery
Author(s) -
AM El-Kasaby,
HM Atef,
AM Helmy,
Mohamed Abo Elnasr
Publication year - 2010
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/1658-354x.71571
Subject(s) - medicine , anesthesia , intubation , effective dose (radiation) , radiology
Cisatracurium in clinical practice is devoid of histamine-induced cardiovascular effects. On the other hand, 2 ED(95) doses of cisatracurium (100 µ g/kg) do not create satisfactory intubating conditions such as those seen with equipotent doses of atracurium. The recommended intubating dose of cisatracurium is 3 ED(95). To understand this discrepancy better, we evaluated the potency and onset of atracurium and cisatracurium.