Open AccessStudy of alloimmunization and autoimmunization in Iranian β-thalassemia major patients
Author(s) -
Kambiz Davari,
Mohammad Soleiman Soltanpour
Publication year - 2016
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.172179
Subject(s) - medicine , thalassemia , antigen , splenectomy , incidence (geometry) , immunology , red blood cell , red cell , autoantibody , rh blood group system , isoantibodies , antibody , blood transfusion , gastroenterology , spleen , physics , optics
Thalassemia is one of the most common monogenic disorders characterized by reduced production of globin chains. Although regular red blood cell (RBC) transfusion support is the main treatment for these patients, it may be associated with complications such as RBC alloimmunization.