Open AccessFatal rhino-orbito-cerebral mucormycosis in a healthy individual
Author(s) -
Rama Krishna Angali,
Anunayi Jeshtadi,
Vivek Anand Namala,
Ashalata Gannepalli
Publication year - 2014
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.151355
Subject(s) - mucormycosis , medicine , diabetic ketoacidosis , ketoacidosis , status epilepticus , cerebral infarction , epilepsy , pediatrics , surgery , diabetes mellitus , psychiatry , type 1 diabetes , endocrinology , ischemia
Rhino-orbital-cerebral zygomycosis is a potentially lethal, opportunistic, fungal infection with protean manifestations, rapid progression, unpredictable course and high mortality. It is associated with angioinvasion and infarction, usually observed in diabetic ketoacidosis, immuno-compromised states and rarely reported in an apparently normal host. We present a case of an18-year-old patient with a chronic, painful, non healing ulcer with necrotic margins over the right side of the face which extended to both orbits involving eyes within a period of 1.5 month. Later he developed severe headache, decreased vision, inability to speak, seizures and status epilepticus with fatal outcome. Awareness of its occurrence in normal patients with prompt diagnosis and appropriate management may improve the outcome and decrease mortality.