
Study of immunohistochemical demonstration of Bcl-2 protein in ameloblastoma and keratocystic odontogenic tumor
Author(s) -
Cs Sindura,
Chaitanya N. Babu,
Vijaya V Mysorekar,
Vinod Kumar
Publication year - 2013
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.119750
Subject(s) - ameloblastoma , keratocystic odontogenic tumor , immunohistochemistry , biology , pathology , medicine , anatomy , odontogenic , maxilla
The Bcl-2 (B-cell lymphoma) gene product also known as apoptotic inhibitor is expressed in many normal and tumor tissues. This Bcl-2 gene protects the cell by blocking postmitotic differentiation from apoptosis, thus maintaining the stem cell pool.