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Evaluation of the effect of locally administered amitriptyline gel as adjunct to local anesthetics in irreversible pulpitis pain
Author(s) -
Ali Akbar Moghadamnia,
M Partovi,
I Mohammadianfar,
Zahra Madani,
Ebrahim Zabihi,
Mahmoud Reza Hamidi,
Mahmoud Baradaran
Publication year - 2009
Publication title -
indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.49047
Subject(s) - amitriptyline , medicine , visual analogue scale , anesthesia , lidocaine , placebo , analgesic , pathology , alternative medicine
Amitriptyline is one of the most common tricyclic antidepressants, which binds to pain sensory nerve fibers close to the sodium channel; hence, it could interact to some degree with receptors of local anesthetics. This study was designed to assess the additional analgesic effects of 2% Amitriptyline local gel administration in irreversible pulpitis pain of the molars.

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