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Reverse masquerade syndrome: Fungal adnexal infection mimicking carcinoma in a HIV-positive patient
Author(s) -
Bipasha Mukherjee,
Raka Chatterjee,
Jyotirmay Biswas
Publication year - 2013
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.119454
Subject(s) - medicine , eyelid , conjunctiva , pathology , biopsy , lesion , carcinoma , periodic acid–schiff stain , grocott's methenamine silver stain , candida albicans , dermatology , staining , radiology , genetics , biology
A known HIV-positive male patient presented with a rapidly progressive ulcerative lesion involving the conjunctiva, lids, and anterior orbit along with a decrease in vision in the right eye. He was on anti retro-viral and anti-tubercular therapy. In view of the clinical features, our provisional clinical diagnosis was a malignant lesion of the eyelid with orbital involvement, possibly squamous cell carcinoma. However, incisional biopsy revealed absence of malignant cells. On Gomori Methenamine Silver staining, plenty of fungal filaments were seen, which was confirmed by culture as Candida albicans. Hence, it turned out to be a case of fungal adnexal infection mimicking carcinoma in a HIV-positive patient. The patient responded well to systemic anti-fungals.

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