Open AccessChronic phenytoin therapy-induced vecuronium resistance
Author(s) -
Lopamudra Chowdhury,
Arpita Laha,
Tamonash Chaudhuri,
Suparna Chatterjee
Publication year - 2011
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.77378
Subject(s) - phenytoin , medicine , pharmacology , epilepsy , psychiatry
This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.