
Mutational characteristics in consecutive passage of rapidly replicating variants of hepatitis A virus strain H2 during cell culture adaptation
Author(s) -
Ningzhu Hu,
Yunzhang Hu,
Hongzhe Shi,
Guodong Liu,
Su Qu
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i5.872
Subject(s) - titer , serial passage , virology , biology , virus , strain (injury) , genome , antigen , viral replication , genetics , gene , anatomy
To investigate the molecular mechanism of cell adaptation and rapid replication of hepatitis A virus strain H2 in KBM17 cells.