Open AccessStudy on the characteristics of intestinal motility of constipation in patients with Parkinson's disease
Author(s) -
Mei Zhang,
Shuang Yang,
Xiaocui Li,
Hongming Zhu,
Pingyu Ding,
Bangyi Li,
Tian-Xu Jia,
Chen Tian
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i11.1055
Subject(s) - constipation , medicine , disease , parkinson's disease , gastroenterology , intestinal motility , motility , enteric nervous system , biology , genetics
Constipation is one of the most important nonmotor symptoms in Parkinson's disease (PD) patients, and constipation of different severities is closely related to the pathogenesis of PD. PD with constipation (PDC) is considered a unique type of constipation, but its mechanism of formation and factors affecting its severity have been less reported. Understanding the gastrointestinal motility characteristics and constipation classification of PDC patients is essential to guide the treatment of PDC. In this study, the colonic transit test and high-resolution anorectal manometry were used to identify the intestinal motility of PDC to provide a basis for the treatment of PDC.