Open AccessOsteopontin is an important mediator of alcoholic liver diseaseviahepatic stellate cell activation
Author(s) -
Devanshi Seth,
Alastair Duly,
Paul C. Kuo,
Geoffrey W. McCaughan,
Paul S. Haber
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i36.13088
Subject(s) - hepatic stellate cell , osteopontin , alcoholic liver disease , in vivo , steatosis , alcoholic hepatitis , cirrhosis , chemistry , cancer research , pathology , medicine , biology , endocrinology , microbiology and biotechnology
To investigate over-expression of Osteopontin (OPN) pathway expression and mechanisms of action in human alcoholic liver disease (ALD), in vivo and in vitro acute alcohol models.