Open AccessPolymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population
Author(s) -
Richard Keld,
Manyi Thian,
Chia-Hao Ma,
Sajid Jamil,
Niraj Kumar,
Yeng Ang
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i34.12212
Subject(s) - methylenetetrahydrofolate reductase , medicine , gastroenterology , vitamin b12 , adenocarcinoma , genotype , genotyping , population , cancer , hyperhomocysteinemia , oncology , risk factor , biology , genetics , environmental health , gene
To identify if methylene tetra-hydrofolatereductase (MTHFR) C677T polymorphisms are associated with oesophageal adenocarcinomas in a Caucasian population and to test whether folic acid and homocysteine levels are linked with cancer risk.