Open AccessGlycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in ratsviaa p53-mediated pathway
Author(s) -
Xiaoling Guo,
Bo Liang,
Xuewei Wang,
Fugang Fan,
Jing Jin,
Rui Lan,
Jinghui Yang,
Xiaochun Wang,
Lei Jin,
Qing Cao
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i24.3781
Subject(s) - carbon tetrachloride , tunel assay , apoptosis , chemistry , subcutaneous injection , intraperitoneal injection , terminal deoxynucleotidyl transferase , sirius red , liver function , h&e stain , ccl4 , hepatocyte , staining , alanine transaminase , endocrinology , medicine , immunohistochemistry , andrology , pharmacology , pathology , biochemistry , organic chemistry , in vitro
To investigate the effect of glycyrrhizic acid (GA) on carbon tetrachloride (CCl4)-induced hepatocyte apoptosis in rats via a p53-dependent mitochondrial pathway.