
Reversal of hyperglycemia in diabetic rats by portal vein transplantation of islet-like cells generated from bone marrow mesenchymal stem cells
Author(s) -
Xiaohong Wu,
Cuiping Liu,
Kuanfeng Xu,
Xiaodong Mao,
Jian Zhu,
Jintao Jiang,
Caili Dai,
Mei Zhang,
Yan Xu,
Chao Liu
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i24.3342
Subject(s) - islet , transplantation , medicine , endocrinology , mesenchymal stem cell , pancreas , stem cell , bone marrow , streptozotocin , insulin , glucagon , biology , diabetes mellitus , pathology , microbiology and biotechnology
To study the capacity of bone marrow mesenchymal stem cells (BM-MSCs) trans-differentiating into islet-like cells and to observe the effect of portal vein transplantation of islet-like cells in the treatment of streptozotocin-induced diabetic rat.