Open AccessDetection of germline mutations of hMLH1 and hMSH2 based on cDNA sequencing in China
Author(s) -
ChaoFu Wang,
Xiao Zhou,
Tai Ming Zhang,
Meng Sun,
Da Shi
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i42.6620
Subject(s) - germline mutation , complementary dna , genetics , biology , germline , exon , missense mutation , mutation , dna sequencing , dna mismatch repair , coding region , microbiology and biotechnology , gene , dna repair
To detect the germline mutations of hMLH1 and hMSH2 based on mRNA sequencing to identify hereditary non-polyposis colorectal cancer (HNPCC) families.