
Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity
Author(s) -
Yuichi Yamazaki
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i38.5966
Subject(s) - liver injury , constitutive androstane receptor , cyp2e1 , carbon tetrachloride , pharmacology , centrilobular necrosis , chemistry , activator (genetics) , receptor , nuclear receptor , enzyme , medicine , biochemistry , cytochrome p450 , organic chemistry , transcription factor , gene
To investigate the precise roles of CAR in CCl(4)-induced acute hepatotoxicity.