Open AccessConstruction and characterization of chimeric BHIV (BIV/HIV-1) viruses carrying the bovine immunodeficiency virusgaggene
Author(s) -
Yingjun Zhu,
Chang Liu,
Xinlei Liu,
Wentao Qiao,
Qimin Chen,
Yi Zeng,
Yi Geng
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i17.2609
Subject(s) - virology , transfection , biology , gene , group specific antigen , hek 293 cells , chimeric gene , virus , fusion protein , fusion gene , chimera (genetics) , microbiology and biotechnology , dna , cell culture , recombinant dna , gene expression , genetics
To explore the possibility of the replacement of the gag gene between human immunodeficiency virus and bovine immunodeficiency virus, to achieve chimeric virions, and thereby gain a new kind of AIDS vaccine based on BHIV chimeric viruses.