Open AccessLoss of heterozygosity on chromosome 10q22-10q23 and 22q11.2-22q12.1 andp53gene in primary hepatocellular carcinoma
Author(s) -
Guoqiang Zhu,
Li Zuo,
Qing Zhou,
Sumei Zhang,
Huaqing Zhu,
Shuyu Gui,
Yuan Wang
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i13.1975
Subject(s) - exon , loss of heterozygosity , biology , gene , tumor suppressor gene , genetics , chromosome 22 , microbiology and biotechnology , chromosome , allele , carcinogenesis
To analyze loss of heterozygosity (LOH) and homozygous deletion on p53 gene (exon2-3, 4 and 11), chromosome 10q22-10q23 and 22q11.2 -22q12.1 in human hepatocellular carcinoma (HCC).