Open AccessMomordica charantia constituents and the anti-proliferative activity against an ovarian cancer cell-line SKOV-3
Author(s) -
Vishal Pundir,
Aditya Chandel
Publication year - 2021
Publication title -
flora and fauna/flora and fauna
Language(s) - English
Resource type - Journals
eISSN - 2456-9364
pISSN - 0971-6920
DOI - 10.33451/florafauna.v27i2pp185-190
Subject(s) - momordica , traditional medicine , in vitro , cancer cell lines , amino acid , chemistry , food science , fruit juice , biology , biochemistry , cancer , cancer cell , medicine , genetics
Momordica charantia fruits contain terpenoidal saponins, phenolic acids, minerals and amino acids, all of which are shown to confer beneficial effects on human health. This study describes a method to conduct qualitative composition analysis of bioactive compounds in the fresh juice of Momordica charantia fruits harvested locally in Jaunpur (Uttar Pradesh, India) grown under traditional farming conditions. Fruit juice extract consisting primarily of phenolic acids, showed presence of 12 compounds. Crude extract inhibited the viability of a platinum resistant ovarian cancer cell-line SKOV-3 in-vitro during 48 hours of treatment.