Clinical Usefulness of Antimicrobial Susceptibility Test for Helicobacter pylori
Author(s) -
Heungsup Sung,
HeeJung Chung,
MiNa Kim,
Gin Hyug Lee
Publication year - 2006
Publication title -
annals of laboratory medicine
Language(s) - English
Resource type - Journals
eISSN - 2234-3814
pISSN - 2234-3806
DOI - 10.3343/kjlm.2006.26.3.179
Subject(s) - metronidazole , clarithromycin , helicobacter pylori , etest , amoxicillin , medicine , drug resistance , antibiotic resistance , antimicrobial , antibiotics , combination therapy , regimen , gastroenterology , microbiology and biotechnology , biology
Antimicrobial resistance of Helicobacter pylori is considered as the main cause of failure of eradication therapy. Because resistance to metronidazole has been reported in 25.8% to 66.2% of H. pylori, a combination of proton pump inhibitors (PPI), amoxicillin, and clarithromycin is currently recommended as a primary therapy. We investigated the prevalence of antimicrobial resistance to the primary drugs and the impact of antimicrobial resistance on eradication rates.
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