Open AccessIncidence and Antibiogram of Acinetobacter Causing Neonatal Sepsis Among Hospitalised Patients
Author(s) -
Syeda Shahnoor Hasina Mamtaz,
Abu Hena Md Saiful Karim Chowdhury,
Gulshan Ara Begum,
Asma Ferdousi,
Mohammad Shahab Uddin
Publication year - 2020
Publication title -
chattagram maa-o-shishu hospital medical college journal
Language(s) - English
Resource type - Journals
eISSN - 2306-4919
pISSN - 2305-7890
DOI - 10.3329/cmoshmcj.v19i1.48797
Subject(s) - acinetobacter , meropenem , cefotaxime , medicine , cefepime , amikacin , ceftazidime , antibiotic sensitivity , ampicillin , ciprofloxacin , microbiology and biotechnology , antibiogram , neonatal sepsis , neonatal intensive care unit , blood culture , levofloxacin , sepsis , antibiotics , imipenem , antibiotic resistance , biology , pediatrics , pseudomonas aeruginosa , bacteria , genetics
Background: Acinetobacter species are typical nosocomial pathogens causinginfections and high mortality, almost exclusively in compromised hospitalizedpatients. Multidrug-resistant Acinetobacter spp. blood infection in the neonatalintensive care unit patients create a great problem in hospital settings. The studywas done to detect prevalence of acinetobacter spp. as the causative agent ofneonatal sepsis with its antibiogram
Materials and methods: A total of 100 clinically suspected neonatal sepsis caseswas enrolled in the study. Bacteriological profile and antibiotic sensitivity pattern ofacinetobacter spp. were done accordingly.
Results: Among the 100 suspected neonatal sepsis cases, 28% were culture positiveand 72% were culture negative. Klebsiella species was the predominant isolatedbacteria which was 53.58% followed by Acinetobacter spp. (14.28%) E. coli(10.72%)Pseudomonas spp. (7.14%) S. aureus (7.14%) & Candida (7.14%). Acinetobacter spp.showed 100% resistant to ampicillin, ciprofloxacin, gentamycin, amikacin,ceftazidime, cefotaxime & cefepime, 75% resistant to meropenem & 50% sensitiveto levofloxacin.
Conclusion: It is essential to conduct periodic bacteriological profile along withroutine antimicrobial sensitivity testing time to time for effective management ofneonatal sepsis.
Chatt Maa Shi Hosp Med Coll J; Vol.19 (1); January 2020; Page 20-23