Open AccessBCL6 inhibition ameliorates resistance to ruxolitinib in <i>CRLF2</i>-rearranged acute lymphoblastic leukemia
Author(s) -
Shinobu Tsuzuki,
Takahiko Yasuda,
Hiroaki Goto,
Naoko Maeda,
Koshi Akahane,
Takeshi Inukai,
Hideyuki Yamamoto,
Sivasundaram Karnan,
Akinobu Ota,
Toshinori Hyodo,
Hiroyuki Konishi,
Yoshitaka Hosokawa,
Hitoshi Kiyoi,
Fumihiko Hayakawa
Publication year - 2022
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2022.280879
Subject(s) - ruxolitinib , bcl6 , cancer research , stat5 , downregulation and upregulation , apoptosis , growth inhibition , jak stat signaling pathway , medicine , immunology , biology , b cell , bone marrow , gene , tyrosine kinase , receptor , germinal center , antibody , biochemistry , myelofibrosis